From 'Accompanying' to 'Leading': Yuyan Instrument's Small Animal Non Invasive Blood Pressure Monitor and Market Revolution
Recently, the tariff war between China and the United States has escalated again, with the US arbitrarily imposing excessively high tariffs on China, seriously violating international economic and trade rules. The State Council Tariff Commission issued a statement on the 11th stating that, with the approval of the State Council, the tariff rate stipulated in the "Announcement of the State Council Tariff Commission on Adjusting the Measures for Imposing Additional Tariffs on Imported Goods Originating in the United States" (Tariff Commission Announcement No. 5 of 2025) will be adjusted from 84% to 125% starting from April 12, 2025. This policy is not only a challenge for the animal research equipment industry, but also a golden window for domestic substitution of imports. In the short term, US research equipment exported to China has lost its market due to soaring prices; In the long run, this is a strategic opportunity for China to break its technological dependence and achieve independent innovation.
The monopoly dilemma of imported equipment: prejudices and truths in scientific research
长期以来，国内小动物无创血压计市场被美国品牌主导，但其设备存在明显功能局限：1. Insufficient measurement accuracy: The measurement error rate of blood pressure in mice weighing less than 20g is high, making it difficult to meet the needs of precise scientific research;
2. Single channel and low efficiency: Traditional equipment mostly uses single channel measurement, which limits the number of animals that can be measured in a single day and slows down the progress of experiments;
3. Complicated operation: The animal fixation device is complex and requires a long time to adapt, which increases the interference of experimental variables.
Technological Breakthrough: Three Revolutionary Breakthroughs of Domestic Blood Pressure Monitor
为捍卫国产科研设备尊严，打破科研人对小动物无创血压计心中的”成见”，玉研仪器基于在动物科研领域的丰富经验，历时多年打磨，经过科学家们的反馈和建议不断优化，推出一款高灵敏度高精度专用于大小鼠的无创血压仪，并经过了市场的苛刻验证。
01. Principle of non-invasive blood flow measurement technology for small animals
市面小动物无创血压计技术原理多为脉搏波法测量法，用充气方式改变鼠尾套内压力，对鼠尾动脉实施压迫（阻断血流）和松解（恢复血流）。当鼠尾套内压力处于动脉血流从完全阻断再到心脏射血能使动脉血流开始贯通时，此时脉搏波从之前的消失情况到出现第一个脉搏波，此波出现时所对应的压力值代表着收缩压。
02. Traditional non-invasive blood pressure measurement pain points for small animals
尽管各个厂商采用的传感器类型不同，但由于小鼠的血流脉搏信号要远弱于大鼠，在测量小鼠血压值方面效果总是差强人意，甚至部分厂商无法测量小鼠血压值。
1.解决方案：NIBP型小动物无创血压计从设计、选型、研发、生产、测试全部由公司研发测试团队一举完成。采用国际先进的光电传感器技术，可检测出微弱的鼠尾脉搏波信号，支持测量大小鼠体重范围15-1000克，测量参数包含：收缩压、平均压、舒张压和心率。
2. Customer value: Blood pressure measurement for large and small mice is guaranteed.
Measurement pain point 2: Most of them are single channel measurement systems, which cannot meet the needs of batch measurement
目前大小鼠无创血压测量只有部分美国进口厂商具有多通道同步测量系统提供选择，国产大小鼠无创血压计多为单通道测量，提供的多通道同步测量系统不能真正做到多个通道同步进行，只能进行多个通道轮流切换进行，时效性不佳。
1.解决方案：针对对于单日测试的动物批次多、数量多的情况，玉研仪器提供多通道测量系统对多只动物进行同步测量，可缩短使用者所需测试时间。可供选择测量系统有：1-9通道测量系统。
2. Customer value: Increased the number of animals measured in a single day.
Measurement pain point 3: Animal fixation is more complicated, and the adaptation time is long
Animal fixation methods often use mouse bags and mouse tails. First, the mouse needs to be stuffed into a mouse net, then the mouse bag is wrapped around the net to expose the tail, and finally the sensor and mouse tail are wrapped around the mouse tail. The process is quite complicated, and the mouse bag requires frequent washing and cleaning.
1. Solution: Use a pure black acrylic material holder to make animals more quiet, with a bracket that is not easy to tilt. Equipped with a pull-out bottom plate connection sensor and fixator, it is convenient to quickly fix animals.
2. Customer value: Reduced animal adaptation time before each test.
In depth analysis: Six core advantages define new industry benchmarks
玉研仪器自主研发的NIBP型小动物无创血压计，以六大核心技术优势重塑行业标准，为科研机构提供从硬件到软件的全方位解决方案。
01. Wide applicability
适用范围广，具备5种传感器和7种规格鼠筒，适用于15-1000g范围大小鼠鼠尾无创血压测量，无论您使用的动物为何种体型，均有合适传感器和配件可供选择。
02. High data accuracy
Red light photoelectric sensor, high sensitivity, accurate and stable data; It also has automatic error recognition, and erroneous data is not included in data statistics, reducing the workload of experimental data post-processing and screening, and further improving research efficiency.
03.温度控制温和
The independent constant temperature chamber design ensures accurate temperature data, comfortable environment, and minimal animal stress response. Data can often be obtained at lower temperatures without worrying about poor data quality caused by animal stress.
04.检测参数全面
Systolic blood pressure, diastolic blood pressure, mean blood pressure, heart rate, automatic statistical data mean and standard deviation; The heart rate range is 0-999bpm, with comprehensive data to meet the needs of research in different fields.
05. Fast testing speed
The testing speed is fast, and in general, animals can start testing after about 10 minutes of adaptation. The duration of a single test does not exceed 20 seconds, which exceeds the testing speed of similar imported products and is at an excellent level in the industry.
06. Experimental high-throughput
High throughput design, software supports up to 9 channels of devices running simultaneously, data synchronization display, no need to switch data windows, "true" multi-channel measurement, greatly improving measurement efficiency.
市场变局：从“替代”到“领跑”的底气
国家“十四五”生物经济发展规划将科研仪器国产化上升为战略任务，明确提出“支持高端科研仪器设备研发制造”，并通过三大举措构建国产替代生态：
1.政策倾斜：中央财政设立专项基金支持国产设备研发，对首台套重大技术装备提供税收优惠和采购补贴；
2.政府采购硬约束：修订相关细则，指出“国产设备能满足需求的，原则上必须采购”，并将国产设备占比纳入地方政府绩效考核；
3.产学研协同攻关：推动高校、科研院所与企业共建联合实验室，针对动物科研设备领域“卡脖子”技术进行集中突破。
02. Customer Value Verification
1. A laboratory at Zhejiang University
2. A laboratory at Nanhua University
3. Laboratory of a certain institution in Guangdong
Defining a new benchmark in the industry with hardcore technology and leading the global scientific research track with Chinese intelligent manufacturing
Yuyan Instrument's non-invasive blood pressure monitor has set a new standard for domestic scientific research equipment with six core advantages: from non-invasive precise measurement to nine channel synchronous efficiency improvement, from fully self-developed technological barriers to national service ecological layout, we provide not only equipment, but also a full cycle scientific research empowerment solution from laboratory to preclinical - making data more accurate, experiments more efficient, and innovation more free.
在国产替代进口的历史浪潮中，我们以硬核创新重新定义科研设备标准，用中国智慧点亮全球实验室的灯火。玉研仪器，让科研未来触手可及。
Self developed core, forging extraordinary strength
Shanghai Yuyan Scientific Instrument Co., Ltd., as a leading manufacturer of scientific research equipment in the industry, has always adhered to the core concept of innovation driven development and self-developed excellence since its establishment in 2010 for 15 years. It is committed to independent research and development and production of scientific instruments. Currently, its product line covers multiple scientific research and application fields such as animal breeding, physiological signal acquisition, and neuroscience research. It not only continuously optimizes and upgrades conventional instruments, but also dares to explore cutting-edge technologies and launches a series of high-end scientific instruments with independent intellectual property rights.
公司研发人员占比40%，拥有传感器、芯片设计、核心算法等科学家团队，在产品落地与运营，市场与学术推广，综合产品方案设计与应用等方面均有专业的团队提供支持，公司拥有可覆盖全国的服务点，技术服务能力强大，客户涵盖清华大学、北京大学、浙江大学、上海交通大学、中国科学院大学、四川大学华西医院、北部战区总医院等国内外一流研究机构、医院。