In neuroscience, pharmacology or disease model research, blood oxygen saturation (SpO₂) monitoring of small animals (such as mice and rats) is a key parameter for evaluating anesthesia depth, respiratory function, and metabolic status.However, traditional methods require repeated blood sampling or rely on complex equipment, resulting in data lag, animal stress, and even experimental interruption.

In a busy animal laboratory, physiological signal acquisition instruments play a vital role.Whether exploring the pathogenesis of a disease or evaluating the efficacy of a new drug, accurate collection and analysis of physiological signals from experimental animals are essential.null null Yuyan Instruments provides various instruments for collecting physiological signals of experimental animals, providing strong support for laboratory physiological signal collection. Today, let us step into this field together, explore the magical instruments used for collecting physiological signals of mice and rats, understand their basic principles, functional characteristics and application fields, and provide strong support for our experimental research.

In the vast world of modern medicine and life science research, blood analysis of experimental animals plays a vital role.It is not only a window for us to understand the health status of organisms, but also an indispensable scientific basis for disease diagnosis and drug development.However, faced with the growing demand for testing and the complex and diverse types of experimental animals, traditional blood analysis methods often seem to be unable to cope with the situation.

There are three ways to administer drugs to mice: subcutaneous injection, intraperitoneal injection, and tail vein injection. Although subcutaneous and intraperitoneal injections are easy to operate, tail vein injection is superior in some research areas that require precise dosage and rapid systemic distribution, such as pharmacokinetics, gene therapy, and tumor models, due to its rapid onset, precise dosage, systemic distribution, and repeatable administration.

In animal experiments, intermittent administration methods such as intraperitoneal injection and subcutaneous injection are still the mainstream methods.Although these methods are simple to operate, they have significant drawbacks in long-term studies: 1. Fluctuation in blood drug concentration: The difference between peak and trough drug concentration after a single injection can be as much as 5-8 times, affecting the accuracy of drug efficacy assessment; 2. Stress interference: Continuous intraperitoneal injection leads to a continuous increase in cortisol levels, which may mask the true effect of the drug; 3. Operational limitations: Dosing at a fixed time each day makes it difficult to conduct circadian rhythm studies, and nighttime operation can easily result in data loss;

In life science and medical research, experimental animals are indispensable and important tools, and drug administration methods are a key link in experimental design.Whether oral, injection, inhalation or topical administration, different administration methods directly affect the accuracy and reliability of experimental results.